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Category: Small Animals

 

Efficacy and safety of enflicoxib for treatment of canine osteoarthritis: A 6-week randomised, controlled, blind, multicentre clinical trial

M. Salichs, L. Badiella, P. Sarasola and J. Homedes | Veterinary Record | September 2021
The aim of this prospective randomised controlled trial was to confirm the safety and efficacy of enflicoxib for the treatment of naturally occurring osteoarthritis (OA) in dogs…

Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK

J.D. Fonseca, D.E. Mavrides, P.A. Graham and T.D. McHugh | Journal of Small Animal Practice | August 2021
The aim of this retrospective study was to investigate the antibiotic resistance of bacterial uropathogens in dogs and cats in the UK…

Using psychopharmacology in the treatment of problem behaviours in dogs and cats

C. Warnes | UK-Vet Companion Animal | October 2021
This review article, written by a veterinary behaviourist, provides an overview of some of the behaviourally-active drugs that are used to treat dogs and cats in the UK and discusses some of the factors that need to be considered when using medication as part of behaviour modification in cats and dogs…

A prospective, randomized, placebo-controlled, double-blinded clinical trial comparing the incidence and severity of gastrointestinal adverse events in dogs with cancer treated with piroxicam alone or in combination with omeprazole or famotidine

M.H. Shaevitz, G.E. Moore and C.M. Fulkerson | Journal of the American Veterinary Medical Association | August 2021
The aim of this randomised placebo-controlled, double-blinded trial, which was carried at a Veterinary Teaching Hospital in the United States and funded by the Veterinary Cancer Society’s Resident Research Award, was to assess the impact of prophylactic administration of omeprazole or famotidine on the incidence and severity of gastrointestinal (GI) adverse events (AEs) in dogs with cancer treated with piroxicam…

Outcomes of nine cats with urinary retention after sacrocaudal luxation managed with long-term urinary diversion

M. Garcia, C. Dumartinet, F. Bernard and A. Bernardé | Veterinary Surgery | August 2021
The aim of this retrospective case series was to document the outcomes of cats with urinary retention following sacrocaudal luxation managed by long-term cystostomy. The study was carried out at the ‘contributing institution’, which is taken to be the authors’ workplace, the Centre Hospitalier Vétérinaire St Martin in France…

Prediction of clinically important acquired cardiac disease without an echocardiogram in large breed dogs using a combination of clinical, radiographic and electrocardiographic variables

S. Wesselowski, S.G. Gordon, N. Meddaugh, A.B. Saunders, J. Häggström, K. Cusack, B.W. Janacek and D.J. Matthews | Journal of Veterinary Cardiology | August 2021
The objectives of this retrospective study were to (1) assess the clinical utility of thoracic radiographs and (2) to explore the potential utility of prediction models incorporating radiographic measurements, physical examination (PE) and electrocardiogram (ECG) to predict clinically important dilated cardiomyopathy (DCM) or myxomatous mitral valve disease (MMVD) in the absence of an echocardiogram in large-breed (LB) dogs…

Vet examining a dog in a clinic

A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab , a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis

M.J. Corral, H. Moyaert, T. Fernandes, M. Escalada, J.K.S. Tena, R. R. Walters and M.R. Stegemann | Veterinary Anaesthesia and Analgesia | August 2021
The aim of this randomized, double-blind, multicentre study was to evaluate the efficacy and safety of bedinvetmab (Librela; Zoetis), compared to a placebo, for the alleviation of pain associated with osteoarthritis in client-owned dogs (n = 287)…

A Golden Retriever lying on a bed

Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs

M. Krautmann, R. Walters, P. Cole, J. Tena, L.M. Bergeron, J. Messamore, D. Mwangi, S. Rai, P. Dominowski, K. Saad, Y. Zhu, M. Guillot and L. Chouinard | The Veterinary Journal | October 2021
This paper describes the laboratory safety evaluation of bedinvetmab based on three integrated laboratory studies in healthy adult laboratory Beagles…

Efficacy and safety of an anti-nerve growth factor antibody (Frunevetmab) for the treatment of degenerative joint disease-associated chronic pain in cats: A multisite pilot field study

M.E. Gruen, J.A.E. Myers and B. D. X. Lascelles | Frontiers in Veterinary Science | May 2021
The aim of this randomised placebo-controlled, double-blinded trial was to evaluate the safety and efficacy of two administration routes of frunevetmab compared to placebo in the treatment of degenerative joint disease (DJD)-associated pain in client-owned cats…

Evaluation of prescribing practices for gabapentin as an analgesic among veterinary professionals

R. Reader, O. Olaitan and E. McCobb | Veterinary Anaesthesia and Analgesia | June 2021
This online survey study aimed to describe the prescribing practice for gabapentin as an analgesic among veterinary primary practitioners and specialists in multiple practice settings in the US and Canada…