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Category: Small Animals

 

Vet examining a dog in a clinic

A prospective, randomized, blinded, placebo-controlled multisite clinical study of bedinvetmab , a canine monoclonal antibody targeting nerve growth factor, in dogs with osteoarthritis

M.J. Corral, H. Moyaert, T. Fernandes, M. Escalada, J.K.S. Tena, R. R. Walters and M.R. Stegemann | Veterinary Anaesthesia and Analgesia | August 2021
The aim of this randomized, double-blind, multicentre study was to evaluate the efficacy and safety of bedinvetmab (Librela; Zoetis), compared to a placebo, for the alleviation of pain associated with osteoarthritis in client-owned dogs (n = 287)…

A Golden Retriever lying on a bed

Laboratory safety evaluation of bedinvetmab, a canine anti-nerve growth factor monoclonal antibody, in dogs

M. Krautmann, R. Walters, P. Cole, J. Tena, L.M. Bergeron, J. Messamore, D. Mwangi, S. Rai, P. Dominowski, K. Saad, Y. Zhu, M. Guillot and L. Chouinard | The Veterinary Journal | October 2021
This paper describes the laboratory safety evaluation of bedinvetmab based on three integrated laboratory studies in healthy adult laboratory Beagles…

Efficacy and safety of an anti-nerve growth factor antibody (Frunevetmab) for the treatment of degenerative joint disease-associated chronic pain in cats: A multisite pilot field study

M.E. Gruen, J.A.E. Myers and B. D. X. Lascelles | Frontiers in Veterinary Science | May 2021
The aim of this randomised placebo-controlled, double-blinded trial was to evaluate the safety and efficacy of two administration routes of frunevetmab compared to placebo in the treatment of degenerative joint disease (DJD)-associated pain in client-owned cats…

Evaluation of prescribing practices for gabapentin as an analgesic among veterinary professionals

R. Reader, O. Olaitan and E. McCobb | Veterinary Anaesthesia and Analgesia | June 2021
This online survey study aimed to describe the prescribing practice for gabapentin as an analgesic among veterinary primary practitioners and specialists in multiple practice settings in the US and Canada…

A cross-sectional survey of UK veterinary practices to determine prevalence of patient stress-reducing and welfare-enhancing approaches believed to be undertaken in companion animal practice

E. Feilberg, C.L. Corridan and L.A. Buckley | Journal of Veterinary Behavior | May-June 2021
The aim of this cross-sectional observational survey-based study was to examine the prevalence of the use of low-stress handling techniques (LSHT), as recommended by key organisations, in UK veterinary practices…

2021 AAFP Feline Senior Care Guidelines

M. Ray, H.C. Carney, B. Boynton, J. Quimby, S. Robertson, K. St Denis, H. Tuzio and B. Wright | Journal of Feline Medicine and Surgery | June 2021
These consensus guidelines provide information for practitioners on all aspects of the care of senior cats…

Evaluation of Pexion® (imepitoin) for treatment of storm anxiety in dogs: A randomised, double-blind, placebo-controlled trial

I. Perdew, C. Emke, B. Johnson, V. Dixit, Y. Song, E.H. Griffith, P. Watson and M.E. Gruen | Veterinary Record | May 2021
The aim of this randomised placebo-controlled, double-blinded study was to assess the efficacy of imepitoin for the treatment of storm anxiety in dogs…

Cavalier Charles Spaniel dog

Non-neoplastic anal sac disorders in UK dogs: Epidemiology and management aspects of a research-neglected syndrome

D.G. O’Neill, A. Hendricks, J. A. Phillips, D.C. Brodbelt, D B. Church and A. Loeffler | Veterinary Record | March 2021
The aim of this retrospective cohort study was to evaluate the prevalence, risk factors and interventions for non-neoplastic anal sac disorders (ASDs) in dogs and to identify any breed associations for ASD…

Vet examine dog eye

Melting corneal ulcers (keratomalacia) in dogs: A 5-year clinical and microbiological study (2014–2018)

A. Tsvetanova, R. M. Powell, K. A. Tsvetanov, K. M. Smith and D. J. Gould | Veterinary Ophthalmology | April 2021
The aim of this retrospective study was to identify bacterial microorganisms associated with melting corneal ulcers (keratomalacia) in dogs and to investigate their prevalence, antimicrobial sensitivity, and clinical outcomes…

Vet choosing medication

A randomised controlled trial to reduce highest priority critically important antimicrobial prescription in companion animals

D.A. Singleton, A. Rayner, B. Brant, S. Smyth, P.J. Noble, A.D. Radford and G.L. Pinchbeck | Nature Communications | March 2021
This randomised controlled trial aimed to test the hypothesis that social norm messaging, via integrated electronic health record (EHR), antimicrobial prescription benchmarking and in-practice educational support, would reduce highest priority critically important antimicrobial (HPCIA) prescription frequency and antimicrobial prescription frequency in general, in a cohort of above average HPCIA-prescribing practices…