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Evaluation of the use of midazolam as a co-induction agent with ketamine for anaesthesia in sedated ponies undergoing field castration

A. Allison, R. Robinson, C. Jolliffe and P.M. Taylor | Equine Veterinary Journal | September 2017
Ketamine is commonly used as an anaesthetic induction agent for equine anaesthesia, but it is a poor muscle relaxant so use of ketamine is frequently combined with a benzodiazepine. Diazepam and midazolam, both benzodiazepine derivatives, are often used to facilitate muscle relaxation in equine anaesthesia. Midazolam has the advantage of being water soluble therefore making it more compatible with other anaesthetic agents. Although the combination of ketamine and a benzodiazepine is generally accepted as giving higher quality of anaesthesia, there are few studies comparing the use of ketamine alone to a ketamine-benzodiazepine co-induction…